Å˽ðÁ«´«Ã½

Female researchers in a laboratory
© Å˽ðÁ«´«Ã½

Reaching everyone, everywhere

Å˽ðÁ«´«Ã½ flagship initiatives

Å˽ðÁ«´«Ã½'s flagship initiatives represent its strategic approaches to address the Region's most pressing health challenges. These initiatives reflect how Å˽ðÁ«´«Ã½'s strategy is implemented practically, and range from purely health initiatives to others that tackle  the financial, industrial, and security aspects of health care in the Americas.

The Elimination Initiative
A strategy to eliminate and eradicate more than 30 diseases

Å˽ðÁ«´«Ã½ launched the Elimination Initiative (EI) in 2019 to accelerate the elimination of more than 30 communicable diseases and related conditions in the Americas by 2030. The year 2024 marked the midpoint of the initiative.

 

Å˽ðÁ«´«Ã½ provides countries and territories with technical assistance, funding mobilization, and policy guidance to achieve disease elimination targets. The EI aligns with the Sustainable Development Goals (SDGs), particularly SDG Target 3.3 of ending epidemics of communicable diseases by 2030.

 

The EI builds on past successes in disease control and elimination. In fact, the Americas became the first region in the world to eliminate rubella, congenital rubella syndrome (both in 2015), and measles (in 2016). Smallpox was eliminated in 1973 (and eradicated in 1980), and polio in 1994.

The COVID-19 pandemic disrupted health interventions and set back progress. However, in 2024, the EI regained momentum to accelerate disease elimination and build on the Region’s past successes.

Key achievements of 2024

mother-to-child transmission of HIV and syphilis

Belize, Jamaica, and Saint Vincent and the Grenadines were certified for eliminating the mother-to-child transmission of HIV and syphilis .

rubella icon

Coverage for the first dose of the measles, mumps, and rubella vaccine increased for the first time since 2019, reaching 87%.

vaccine icon

Coverage for diphtheria, tetanus toxoid, and pertussis reached 86% for the third dose.

cervix icon

Cervical cancer elimination efforts were expanded through human papillomavirus vaccination and improved screening.

hospital icon

Continued investment in health infrastructure, surveillance, and treatment is needed to sustain elimination gains.

digital tools icon

Innovative strategies, such as digital health tools and genomic surveillance, are being adopted to track disease transmission.

measles icon

The Region of the Americas was reverified as free of endemic measles in November 2024, thanks to the efforts made by Member States to increase vaccination coverage, strengthen surveillance and rapid response to imported cases.

Despite these accomplishments, Å˽ðÁ«´«Ã½ continues to emphasize the importance of maintaining high vaccination coverage and robust epidemiological surveillance to prevent the reestablishment of endemic measles or rubella virus transmission. The recent identification of measles clusters and cases in some countries also underscores the need for ongoing vigilance and rapid response activities. Of particular relevance is the need to avoid complacency in vaccination efforts for diseases like polio, which was eliminated in the Region 30 years ago but is still prevalent in other parts of the world and, therefore, poses a risk of reintroduction through travelers.

A key component of the EI is the populations that it targets. Neglected infectious diseases and zoonoses affect populations in vulnerable situations that lack sufficient access to integrated health services. These populations include children, rural populations, indigenous communities, women of African descent, LGBTQ+ persons, migrants, and incarcerated people.

Given such circumstances, the EI aims not just to eliminate and sustain the elimination targets over time, but to improve the quality of people's lives by guaranteeing access to integrated health services. This includes, but is not limited to:

    • Expanding vaccination campaigns, early diagnosis, and improved treatment access;
    • Strengthening health systems and universal health coverage;
    • Enhancing primary health care services to detect and treat diseases early;
    • Promoting integrated and sustainable health policies.

Among the diseases targeted, the most relevant are:

1. Diseases preventable by vaccination

• Bacterial meningitis
• Maintaining the elimination of measles, rubella, congenital rubella syndrome, poliomyelitis, and neonatal tetanus

2. Neglected infectious diseases and zoonoses

• Chagas disease
• Leprosy
• Trachoma
• Schistosomiasis
• Intestinal parasites
• Lymphatic filariasis
• Human rabies transmitted by dogs
• Hydatidosis

3. Vector-borne diseases

• Malaria
• Yellow fever

4. Diseases transmitted from mother to child

• Hepatitis B
• Syphilis
• HIV
• Chagas disease

5. Sexually transmitted infections and viral hepatitis

• HIV/AIDS
• Syphilis and other sexually transmitted infections
• Viral hepatitis

6. Other priority conditions and diseases

• Cervical cancer caused by human papillomavirus
• Cholera
• Tuberculosis

A history of disease elimination successes

For over 122 years, Å˽ðÁ«´«Ã½ and the countries and territories of the Americas have played a key role in realizing historic disease elimination achievements.

Explore Timeline →

Digital transformation

The digital revolution is transforming public health in the Americas, enhancing surveillance, healthcare delivery and accessibility, efficiency, and patient-centered care.

 

However, digital transformation demands massive cultural changes and major investments alongside improvement in the Region’s human capital. This transformation must be implemented looking at all opportunities, especially those associated with closing gaps such as barriers in access to care, while at the same time always looking to potential inequalities that may arise or increase due to the digital divide; for instance, urban and rural regions, age, and socioeconomic and ethnic groups.

As digital health transformation is being positioned at the highest level of technical and political agendas, Å˽ðÁ«´«Ã½ is leading efforts to accelerate the process and to close gaps and promote data-driven decision-making to improve health outcomes. To that end, it has launched a number of initiatives to promote the digital transformation of the health sector in the Region.

One critical element of this approach is strategic partnerships. The digital transformation is a complex process that requires not only massive resource mobilization and expertise, but also a whole-of-government approach and the harmonic digital transformation of all sectors, an issue that was highlighted and prioritized at the G20 meeting in Brazil in September 2024. Although Å˽ðÁ«´«Ã½ works with numerous organizations and institutions in both the private, government, and multilateral realms, its collaboration with the Inter-American Development Bank (IDB) plays a special role in terms of digital strategies and capabilities at regional, subregional, and national levels.

Under the agreement, both organizations deliver technical, financial, and operational assistance to provide digital health tools to improve healthcare access and coverage, and make evidence-based public health decisions.

The collaboration between Å˽ðÁ«´«Ã½ and the IDB goes beyond technology. It includes working together to strengthen countries’ capacity to prepare and respond to health emergencies and disasters. This entails activities such as collaborating to support countries in the implementation of voluntary Joint External Evaluations of core capacities of the International Health Regulations, as well as in the preparation of technical proposals for submission to the Pandemic Fund.

The Pan American Highway for Digital Health

In October 2024, Å˽ðÁ«´«Ã½ and the IDB formally launched the Pan American Highway for Digital Health. The initiative is partly built on the preexisting Information Systems for Health initiative. However, it embraces the challenges and opportunities created by the new technologies and incorporates the lessons of the COVID-19 pandemic.

The Pan American Highway for Digital Health focuses on the technical issues posed by the adoption of digital technologies, especially with regard to:

 

  • Interoperability: to facilitate the seamless flow of health data among different countries and facilitate the population’s access to the information they need

  • Digital health infrastructure: to construct solid foundations for digital health systems – including infrastructure, governance, and services – and human capital

  • Pandemic preparedness: to apply the lessons of COVID-19, when technology became a critical tool to fight the pandemic

Building on preexisting capabilities

Health worker digital health
© Shutterstock (pixelheadphoto digitalskillet)

In addition to these actions, in 2024, Å˽ðÁ«´«Ã½ reinforced and expanded a number of actions launched in previous years.

One of the most relevant of those initiatives is an already operational, open-source digital platform â€“ Å˽ðÁ«´«Ã½ All-in-One Telehealth Platform â€“ to make telehealth an integral part of the health service delivery networks and to bring telehealth services to remote populations in the Region, making telemedicine the new normal for healthcare workers and patients, especially those with chronic diseases.

Å˽ðÁ«´«Ã½ has also created the Digital Transformation Toolkit, a web page that provides managerial, technical, communication, knowledge, and academic resources. Its users range from health professionals and decision-makers to the general public. Its objective is to give practical answers to day-to-day issues in the use of information technology, especially in terms of strengthening health information systems and ensuring universal access to quality data and digital health tools. Additionally, Å˽ðÁ«´«Ã½ is prioritizing efforts toward the rapid adoption of artificial intelligence in public health, and is actively supporting countries to be better prepared for potential cyber-attack incidents in the health sector.

Better Care for NCDs

woman doing physical exercise
© FG Trade Latin/Getty Images
  • NCDs account for 38% of premature deaths and 65% of all deaths in the Americas, and eventually expected to exceed 80% of all deaths.
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  • Cardiovascular diseases, cancer, diabetes, and chronic respiratory diseases are the leading causes of NCD deaths in the Americas. Especially worrisome is the dramatic increase of diabetes prevalence in Latin America and the Caribbean, driven largely by the high rates of obesity.
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  • Å˽ðÁ«´«Ã½ estimates that approximately 40% of deaths related to NCDs in the Region could be prevented through primary prevention, early diagnosis and better access to continuous care and treatment, much of which can be delivered through primary health care.

 

The year 2024 was the first full year of implementation of the initiative Better Care for NCDs: Accelerating actions in primary health care, which aims to expand access to NCD services by integrating them into the primary health care (PHC) systems of the Region's countries and territories.

NCDs have dramatically grown in importance as factors of public health risk, and economic impact due to loss in workforce, productivity and health care costs. By tackling them, Å˽ðÁ«´«Ã½ has intervened in the most important cause of death and disabilities in the Americas, which also have a strong impact on the economies of the countries and communities.

Addressing NCDs involves promoting public health policies to reduce the common risk factors – tobacco use, harmful use of alcohol, physical inactivity, and unhealthy diets – and also strengthening health systems to provide quality care for NCDs in PHC, with referral systems for higher level care, along with surveillance and monitoring.

An estimated 240 million people are living with NCDs and a significant proportion remain undiagnosed and untreated. To address this gap in NCD diagnosis and treatment, Å˽ðÁ«´«Ã½ has encouraged its Member States to adopt the Better Care for NCDs initiative.

As with many other Å˽ðÁ«´«Ã½ initiatives, Better Care for NCDs relies on PHC services, as these are considered the best way to reach the majority of people and communities for common health problems that require continuous treatment, such as NCDs.

The targeted areas are:

  • Cardiovascular diseases
  • Diabetes
  • Chronic respiratory diseases
  • Cervical cancer prevention (HPV immunization) and screening
  • Health promotion, counseling, and education

Fighting NCDs is a complex task. It demands permanent monitoring of patients, preventive care, multidisciplinary approaches, integration of services, and introducing changes in lifestyle.

This entails:
  • Understanding and meeting population needs for improved NCD diagnosis and treatment, including self-care
  • Community outreach
  • Standardized guidelines
  • Increased access to essential NCD medicines and technologies
  • Workforce training and continuous education
  • A life course approach

Better Care for NCDs showcases how Å˽ðÁ«´«Ã½ uses its resources in an integrated fashion and builds up new projects on preexisting ones.

Regional Revolving Funds


In terms of integration and coordination, the initiative has the support of Å˽ðÁ«´«Ã½'s Regional Revolving Funds (RRFs) in terms of expanding the availability of essential NCD medicines and technologies.

Access to high-quality, affordable medicines, diagnostics, and equipment to treat:

Diabetes

Cancer

Cardiovascular diseases

Chronic respiratory diseases

HEARTS


Better Care for NCDs builds on previously existing programs such as HEARTS in the Americas, designed to improve hypertension control through strengthened primary care by enhancing managerial and clinical practices, improving access and quality of care for hypertension. Better Care for NCDs and HEARTS are complementary initiatives that reinforce each other.

  • In 2024, the number of PHC centers implementing HEARTS surpassed 7100, providing treatment to 5.7 million adults with hypertension, of whom 63% are controlled.
  • By 2024, 33 countries in the Americas had committed to integrating HEARTS into their PHC networks.
  • Hearts is part of the Better Care for NCDs initiatives that focuses on hypertension control, a key risk factor for cardiovascular diseases.

Regional Revolving Funds
Helping countries to ensure that everyone has access to the health supplies they need

Å˽ðÁ«´«Ã½ worker talking with a man and a child
© Å˽ðÁ«´«Ã½

The Regional Revolving Funds (RRFs) are technical cooperation mechanisms that enable countries in the Americas to access quality supplies at affordable prices in a timely and transparent way. Specifically, they enable access to:

  • Vaccines, cold boxes, and syringes

  • Essential medicines

  • Medical equipment

 

The RRFs consist of two different mechanisms to obtain the best possible conditions for Member States:

Revolving Fund for Access to Vaccines

It is aimed at enabling the Americas to access quality vaccines and immunization related supplies.

Strategic Fund for Public Health Supplies

For quality essential medicines, health supplies, and health technologies in general.

 

The year 2024 was a critical one for the RRFs in terms of:

Their growth to increase impact

In 2024, the Revolving Fund for Access to Vaccines increased its support by 7% when compared to 2023, rising to USD 691.4 million; the Strategic Fund for Public Health Supplies increased its support by 11%, rising to USD 122 million.

Their new priorities, to better attend to the needs of Member States

In 2024, Å˽ðÁ«´«Ã½ Member States restructured the RRFs' priorities to increase healthcare security and resilience in the Region through a resolution. The restructuring is largely a consequence of the lessons learned during COVID-19.


Enhancing the Region’s industrial and technological independence

Thanks to their ability to consolidate regional demand and facilitate partnerships, the RRFs play a critical role in creating ecosystems that, in turn, can enhance access in the Region.

Agreement details


After months of negotiation in 2024, an agreement was reached in January 2025:

Pfizer will transfer to Sinergium Biotech the technology and know-how to produce PCV20.

The RRFs will distribute the vaccine to other countries in the Region.

By consolidating the demand of the whole region for the next years, Å˽ðÁ«´«Ã½ offers suppliers predictability, accuracy, and economies of scale, which contributes to significantly reducing the risk of the investment.

Consequently, Pfizer proposed a deal with the most competitive price for PCV20 it offers in the world.

Building on a history of success


This is the most recent large project that the RRFs have helped to bring to the Region, but it is far from being a one-off success.

The RRFs have been critical in:

  • Assessing the demand for vaccines, the supply chain, the distribution mechanism, and the cost of the development and delivery of the mRNA COVID-19 vaccines in the Region. As the RRFs have been the backbone of decades of Å˽ðÁ«´«Ã½'s work in forecasting and providing access to vaccines, medicines and essential health supplies, they were thus instrumental in this process;
  • Contributing to the elimination of polio and rubella;
  • Avoiding supply disruptions during the COVID-19 pandemic.

Regional Innovation and Production of Health Technologies
Strengthening regional resilience and equitable access

Vaccine production process against COVID-19 of the Oswaldo Cruz Foundation's Institute of Immunological Technology (Bio-Manguinhos/Fiocruz)
© Å˽ðÁ«´«Ã½

The Region of the Americas has important manufacturing capacities but regional access to these health technologies is limited, and we still face important dependency on external essential health technologies and inputs that negatively impact equitable access and regional resilience:

6x

more pharmaceutical imports

Latin America and the Caribbean import six times more pharmaceutical products than they export

80x

more vaccines imported

For vaccines, the difference rises to 80 times more imports

Limited interregional access

Only 13% of pharmaceutical imports come from within the Region

Only 7% of vaccine production is regional

Less than 7% of vaccines procured by Å˽ðÁ«´«Ã½ Regional Revolving Fund are from regional producers

These structural weaknesses became painfully evident during the COVID-19 pandemic, when regional needs and global demand collided with widespread supply chain disruptions. The Region experienced severe shortages and inequitable access to vaccines and other health technologies, highlighting the urgent need for greater regional innovation and manufacturing capacities.

In response, in 2021, the Å˽ðÁ«´«Ã½ 59th Directing Council approved the policy document "Increasing production capacity for essential medicines and health technologies" and the corresponding resolution CD59.R3. These documents provide a common and sustainable framework with prioritized strategic lines of action to orient and guide the countries of the Region in their work. Implementing this mandate, in 2023 Å˽ðÁ«´«Ã½ launched the Special Program, Innovation and Regional Production Platform.

A strategy for health security and access

The Å˽ðÁ«´«Ã½ Innovation and Regional Production Platform focuses on four strategic pillars:

  • Promoting research, innovation, and production of strategic technologies. Supporting countries and innovators to develop and manufacture essential health technologies, with a focus on mRNA vaccine platforms
  • Strengthening regional ecosystems. Building enabling environments for innovation and production through regulatory cooperation, workforce development, policy frameworks and resilient supply chains
  • Generating and disseminating technical information to support evidence-based decision making
  • Facilitating multisectoral dialog and cooperation. Engaging governments, the private sector, academia, civil society, and international organizations, and promoting dialogues, partnerships and collaborations with global and regional partners.

The power of regional coordination

A key advantage of Å˽ðÁ«´«Ã½'s approach is leveraging existing regional mechanisms like its Regional Revolving Funds. These mechanisms consolidate regional demand, providing predictability for manufacturers, and creating economies of scale that reduce prices. In 2024 Member States added new flexibilities to the Å˽ðÁ«´«Ã½ Regional Revolving Funds to promote local production. In 2024, this coordinated approach facilitated the agreement between Pfizer, Argentina's Sinergium Biotech, and Å˽ðÁ«´«Ã½.

Zero Preventable Maternal Deaths

Pregnant woman smiling
© Å˽ðÁ«´«Ã½
  • The maternal mortality ratio (MMR) is a persistent indicator of health risk. Since 2015, the MMR has been steadily increasing in Latin America and the Caribbean, and COVID-19 has dramatically worsened it.
7200
Every year, about 7200 women in the Region die while giving birth or because of pregnancy complications. This equates to almost 20 deaths every day.
90%
6500 (90%) of those fatalities could be prevented.

This ongoing situation complicates efforts to achieve the regional goal of the Å˽ðÁ«´«Ã½â€™s Sustainable Health Agenda for the Americas of 30 deaths per 100 000 live births by 2030, launched by the Region's countries in 2017 and endorsed by Å˽ðÁ«´«Ã½. Achieving that level would be necessary to reach SDG Target 3.1 of a global MMR of 70 by 2030.


A call for action

  • In June 2024, Å˽ðÁ«´«Ã½’s Director made a call for action and released a strategy to accelerate the reduction and address the main structural challenges to maternal health. The strategy includes six strategic lines of action and identifies 12 prioritized countries.

 

12
The Plurinational State of Bolivia, Brazil, Colombia, Dominican Republic, Guatemala, Haiti, Honduras, Jamaica, Mexico, Paraguay, Peru and the Bolivarian Republic of Venezuela are the 12 prioritized countries in Å˽ðÁ«´«Ã½â€™s call to action.

The six strategic lines of action are:

1. Governance

Strengthen governance and stewardship in health and maternal health management.

2. Access

Expand and strengthen the first level of care, prioritizing territories and populations with high MMR and maternal mortality.

3. Networks

Strengthen health service networks with an emphasis on maternal, sexual, and reproductive health care.

4. Quality

Ensure the quality of maternal, sexual, and reproductive health care in integrated health service networks.

5. Workforce

Ensure that there are sufficient, well-distributed, trained, equipped, and motivated human resources for health.

6. Empowerment

Empower women, families, and communities for health care and enforceability of sexual and reproductive rights.


The Å˽ðÁ«´«Ã½ Call for Action also emphasizes other essential conditions to reduce maternal mortality in the Region:

  • Strong political commitment with adequate funding that prioritizes women's health;
  • Intersectoral collaboration to address social, cultural, economic and legal barriers to maternal healthcare access;
  • Effective social mobilization strategies that engage civil society to increase visibility of maternal health issues and build social capital.

To achieve the ambitious goal of reducing maternal deaths to fewer than 30 per 100 000 live births by 2030, the call to action has a multipronged strategy centered on PHC:

  • PHC is the best tool to deliver preventive, health-promoting, life-course-based medical attention.
  • The actions focus on women, families, and communities.

PHC also has more flexibility and understanding of the specific health situation of each community.

  • This is of critical importance as mortality during pregnancy and childbirth is heavily influenced by a number of factors, such as geography (rural vs. urban populations), socioeconomic situation, or ethnicity.

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