Å˽ðÁ«´«Ã½'s flagship initiatives represent its strategic approaches to address the Region's most pressing health challenges. These initiatives reflect how Å˽ðÁ«´«Ã½'s strategy is implemented practically, and range from purely health initiatives to others that tackle  the financial, industrial, and security aspects of health care in the Americas.
Å˽ðÁ«´«Ã½ provides countries and territories with technical assistance, funding mobilization, and policy guidance to achieve disease elimination targets. The EI aligns with the Sustainable Development Goals (SDGs), particularly SDG Target 3.3 of ending epidemics of communicable diseases by 2030.
The EI builds on past successes in disease control and elimination. In fact, the Americas became the first region in the world to eliminate rubella, congenital rubella syndrome (both in 2015), and measles (in 2016). Smallpox was eliminated in 1973 (and eradicated in 1980), and polio in 1994.
The COVID-19 pandemic disrupted health interventions and set back progress. However, in 2024, the EI regained momentum to accelerate disease elimination and build on the Region’s past successes.
Belize, Jamaica, and Saint Vincent and the Grenadines were certified for eliminating the mother-to-child transmission of HIV and syphilis .
Coverage for the first dose of the measles, mumps, and rubella vaccine increased for the first time since 2019, reaching 87%.
Coverage for diphtheria, tetanus toxoid, and pertussis reached 86% for the third dose.
Cervical cancer elimination efforts were expanded through human papillomavirus vaccination and improved screening.
Continued investment in health infrastructure, surveillance, and treatment is needed to sustain elimination gains.
Innovative strategies, such as digital health tools and genomic surveillance, are being adopted to track disease transmission.
The Region of the Americas was reverified as free of endemic measles in November 2024, thanks to the efforts made by Member States to increase vaccination coverage, strengthen surveillance and rapid response to imported cases.
Despite these accomplishments, Å˽ðÁ«´«Ã½ continues to emphasize the importance of maintaining high vaccination coverage and robust epidemiological surveillance to prevent the reestablishment of endemic measles or rubella virus transmission. The recent identification of measles clusters and cases in some countries also underscores the need for ongoing vigilance and rapid response activities. Of particular relevance is the need to avoid complacency in vaccination efforts for diseases like polio, which was eliminated in the Region 30 years ago but is still prevalent in other parts of the world and, therefore, poses a risk of reintroduction through travelers.
A key component of the EI is the populations that it targets. Neglected infectious diseases and zoonoses affect populations in vulnerable situations that lack sufficient access to integrated health services. These populations include children, rural populations, indigenous communities, women of African descent, LGBTQ+ persons, migrants, and incarcerated people.
Given such circumstances, the EI aims not just to eliminate and sustain the elimination targets over time, but to improve the quality of people's lives by guaranteeing access to integrated health services. This includes, but is not limited to:
• Bacterial meningitis
• Maintaining the elimination of measles, rubella, congenital rubella syndrome, poliomyelitis, and neonatal tetanus
• Chagas disease
• Leprosy
• Trachoma
• Schistosomiasis
• Intestinal parasites
• Lymphatic filariasis
• Human rabies transmitted by dogs
• Hydatidosis
• Malaria
• Yellow fever
• Hepatitis B
• Syphilis
• HIV
• Chagas disease
• HIV/AIDS
• Syphilis and other sexually transmitted infections
• Viral hepatitis
• Cervical cancer caused by human papillomavirus
• Cholera
• Tuberculosis
For over 122 years, Å˽ðÁ«´«Ã½ and the countries and territories of the Americas have played a key role in realizing historic disease elimination achievements.
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However, digital transformation demands massive cultural changes and major investments alongside improvement in the Region’s human capital. This transformation must be implemented looking at all opportunities, especially those associated with closing gaps such as barriers in access to care, while at the same time always looking to potential inequalities that may arise or increase due to the digital divide; for instance, urban and rural regions, age, and socioeconomic and ethnic groups.
As digital health transformation is being positioned at the highest level of technical and political agendas, Å˽ðÁ«´«Ã½ is leading efforts to accelerate the process and to close gaps and promote data-driven decision-making to improve health outcomes. To that end, it has launched a number of initiatives to promote the digital transformation of the health sector in the Region.
One critical element of this approach is strategic partnerships. The digital transformation is a complex process that requires not only massive resource mobilization and expertise, but also a whole-of-government approach and the harmonic digital transformation of all sectors, an issue that was highlighted and prioritized at the G20 meeting in Brazil in September 2024. Although Å˽ðÁ«´«Ã½ works with numerous organizations and institutions in both the private, government, and multilateral realms, its collaboration with the Inter-American Development Bank (IDB) plays a special role in terms of digital strategies and capabilities at regional, subregional, and national levels.
New agreement
Based on the lessons learned on the Information Systems for Health initiative, in April 2024, Å˽ðÁ«´«Ã½ and the IDB signed an agreement with three objectives:
Under the agreement, both organizations deliver technical, financial, and operational assistance to provide digital health tools to improve healthcare access and coverage, and make evidence-based public health decisions.
The collaboration between Å˽ðÁ«´«Ã½ and the IDB goes beyond technology. It includes working together to strengthen countries’ capacity to prepare and respond to health emergencies and disasters. This entails activities such as collaborating to support countries in the implementation of voluntary Joint External Evaluations of core capacities of the International Health Regulations, as well as in the preparation of technical proposals for submission to the Pandemic Fund.
In October 2024, Å˽ðÁ«´«Ã½ and the IDB formally launched the Pan American Highway for Digital Health. The initiative is partly built on the preexisting Information Systems for Health initiative. However, it embraces the challenges and opportunities created by the new technologies and incorporates the lessons of the COVID-19 pandemic.
The Pan American Highway for Digital Health focuses on the technical issues posed by the adoption of digital technologies, especially with regard to:
Interoperability: to facilitate the seamless flow of health data among different countries and facilitate the population’s access to the information they need
Digital health infrastructure: to construct solid foundations for digital health systems – including infrastructure, governance, and services – and human capital
Pandemic preparedness: to apply the lessons of COVID-19, when technology became a critical tool to fight the pandemic
In addition to these actions, in 2024, Å˽ðÁ«´«Ã½ reinforced and expanded a number of actions launched in previous years.
One of the most relevant of those initiatives is an already operational, open-source digital platform – Å˽ðÁ«´«Ã½ All-in-One Telehealth Platform – to make telehealth an integral part of the health service delivery networks and to bring telehealth services to remote populations in the Region, making telemedicine the new normal for healthcare workers and patients, especially those with chronic diseases.
Å˽ðÁ«´«Ã½ has also created the Digital Transformation Toolkit, a web page that provides managerial, technical, communication, knowledge, and academic resources. Its users range from health professionals and decision-makers to the general public. Its objective is to give practical answers to day-to-day issues in the use of information technology, especially in terms of strengthening health information systems and ensuring universal access to quality data and digital health tools. Additionally, Å˽ðÁ«´«Ã½ is prioritizing efforts toward the rapid adoption of artificial intelligence in public health, and is actively supporting countries to be better prepared for potential cyber-attack incidents in the health sector.
The year 2024 was the first full year of implementation of the initiative Better Care for NCDs: Accelerating actions in primary health care, which aims to expand access to NCD services by integrating them into the primary health care (PHC) systems of the Region's countries and territories.
NCDs have dramatically grown in importance as factors of public health risk, and economic impact due to loss in workforce, productivity and health care costs. By tackling them, Å˽ðÁ«´«Ã½ has intervened in the most important cause of death and disabilities in the Americas, which also have a strong impact on the economies of the countries and communities.
Addressing NCDs involves promoting public health policies to reduce the common risk factors – tobacco use, harmful use of alcohol, physical inactivity, and unhealthy diets – and also strengthening health systems to provide quality care for NCDs in PHC, with referral systems for higher level care, along with surveillance and monitoring.
An estimated 240 million people are living with NCDs and a significant proportion remain undiagnosed and untreated. To address this gap in NCD diagnosis and treatment, Å˽ðÁ«´«Ã½ has encouraged its Member States to adopt the Better Care for NCDs initiative.
As with many other Å˽ðÁ«´«Ã½ initiatives, Better Care for NCDs relies on PHC services, as these are considered the best way to reach the majority of people and communities for common health problems that require continuous treatment, such as NCDs.
TThe initiative has three overall objectives:
Fighting NCDs is a complex task. It demands permanent monitoring of patients, preventive care, multidisciplinary approaches, integration of services, and introducing changes in lifestyle.
Better Care for NCDs showcases how Å˽ðÁ«´«Ã½ uses its resources in an integrated fashion and builds up new projects on preexisting ones.
The Regional Revolving Funds (RRFs) are technical cooperation mechanisms that enable countries in the Americas to access quality supplies at affordable prices in a timely and transparent way. Specifically, they enable access to:
Vaccines, cold boxes, and syringes
Essential medicines
Medical equipment
It is aimed at enabling the Americas to access quality vaccines and immunization related supplies.
For quality essential medicines, health supplies, and health technologies in general.
In 2024, the Revolving Fund for Access to Vaccines increased its support by 7% when compared to 2023, rising to USDÂ 691.4 million; the Strategic Fund for Public Health Supplies increased its support by 11%, rising to USD 122 million.
In 2024, Å˽ðÁ«´«Ã½ Member States restructured the RRFs' priorities to increase healthcare security and resilience in the Region through a resolution. The restructuring is largely a consequence of the lessons learned during COVID-19.
Thanks to their ability to consolidate regional demand and facilitate partnerships, the RRFs play a critical role in creating ecosystems that, in turn, can enhance access in the Region.
The year 2024 witnessed a powerful collaboration between the United States’ pharmaceutical company Pfizer, Argentina's Sinergium Biotech, Å˽ðÁ«´«Ã½, and the Government of Argentina.
The goal was to produce the 20-valent pneumococcal conjugate vaccine (PCV20) in Argentina and to distribute it to other countries in the Region. This vaccine will help reduce the burden of pneumococcal diseases, offering protection for vulnerable populations throughout the life course, including children, people with comorbidities, and the older persons. Å˽ðÁ«´«Ã½, Sinergium and Pfizer signed an agreement for the distribution of the vaccines through the RRFs.
The Region of the Americas has important manufacturing capacities but regional access to these health technologies is limited, and we still face important dependency on external essential health technologies and inputs that negatively impact equitable access and regional resilience:
Latin America and the Caribbean import six times more pharmaceutical products than they export
For vaccines, the difference rises to 80 times more imports
Only 13% of pharmaceutical imports come from within the Region
Less than 7% of vaccines procured by Å˽ðÁ«´«Ã½ Regional Revolving Fund are from regional producers
These structural weaknesses became painfully evident during the COVID-19 pandemic, when regional needs and global demand collided with widespread supply chain disruptions. The Region experienced severe shortages and inequitable access to vaccines and other health technologies, highlighting the urgent need for greater regional innovation and manufacturing capacities.
In response, in 2021, the Å˽ðÁ«´«Ã½ 59th Directing Council approved the policy document "Increasing production capacity for essential medicines and health technologies" and the corresponding resolution CD59.R3. These documents provide a common and sustainable framework with prioritized strategic lines of action to orient and guide the countries of the Region in their work. Implementing this mandate, in 2023 Å˽ðÁ«´«Ã½ launched the Special Program, Innovation and Regional Production Platform.
The Å˽ðÁ«´«Ã½ Innovation and Regional Production Platform focuses on four strategic pillars:
A key advantage of Å˽ðÁ«´«Ã½'s approach is leveraging existing regional mechanisms like its Regional Revolving Funds. These mechanisms consolidate regional demand, providing predictability for manufacturers, and creating economies of scale that reduce prices. In 2024 Member States added new flexibilities to the Å˽ðÁ«´«Ã½ Regional Revolving Funds to promote local production. In 2024, this coordinated approach facilitated the agreement between Pfizer, Argentina's Sinergium Biotech, and Å˽ðÁ«´«Ã½.
This ongoing situation complicates efforts to achieve the regional goal of the Å˽ðÁ«´«Ã½â€™s Sustainable Health Agenda for the Americas of 30 deaths per 100 000 live births by 2030, launched by the Region's countries in 2017 and endorsed by Å˽ðÁ«´«Ã½. Achieving that level would be necessary to reach SDG Target 3.1 of a global MMR of 70 by 2030.
Strengthen governance and stewardship in health and maternal health management.
Expand and strengthen the first level of care, prioritizing territories and populations with high MMR and maternal mortality.
Strengthen health service networks with an emphasis on maternal, sexual, and reproductive health care.
Ensure the quality of maternal, sexual, and reproductive health care in integrated health service networks.
Ensure that there are sufficient, well-distributed, trained, equipped, and motivated human resources for health.
Empower women, families, and communities for health care and enforceability of sexual and reproductive rights.
To achieve the ambitious goal of reducing maternal deaths to fewer than 30 per 100 000 live births by 2030, the call to action has a multipronged strategy centered on PHC:
PHC also has more flexibility and understanding of the specific health situation of each community.